Human neural stem cells normalize rat behavior after hypoxia.

O V Podgornyi; I V Kheifets; M A Aleksandrova; E V Loseva; A V Revishchin; R A Poltavtseva; M V Marey; L I Korochkin; G T Sukhikh

doi:10.1023/b:bebm.0000035126.42951.44

PubMed · 15452598

Human neural stem cells normalize rat behavior after hypoxia.

O V Podgornyi·I V Kheifets·M A Aleksandrova·E V Loseva·A V Revishchin·R A Poltavtseva·M V Marey·L I Korochkin·G T Sukhikh

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Abstract

Transplants of cultured neural stem cells from human brain survived, retained multipotent activity, and produced a neuroprotective effect on degenerating neurons in the brain of adult rats subjected to hypoxic hypoxia. They normalized animal behavior and improved conditioning in two-way avoidance response paradigm in a shuttle box.

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Animals Behavior, Animal Cells, Cultured Female Humans Hypoxia Motor Activity Neurons Rats Rats, Wistar Stem Cell Transplantation Stem Cells Transplantation, Heterologous Journal Article Research Support, Non-U.S. Gov't

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O V Podgornyi, I V Kheifets, M A Aleksandrova, E V Loseva, A V Revishchin, R A Poltavtseva, M V Marey, L I Korochkin, G T Sukhikh. 2004. Human neural stem cells normalize rat behavior after hypoxia.. https://doi.org/10.1023/b%3Abebm.0000035126.42951.44

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