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PubMed · 15606649

Sensitization to propolis in 1255 children undergoing patch testing.

Francesca Giusti·Roberta Miglietta·Patrizia Pepe·Stefania Seidenari
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Abstract

To investigate the frequency and the features of contact sensitization to propolis in children, we patch tested 1255 consecutive children suspected of allergic contact dermatitis with propolis 20% petrolatum over an 8-year period (1995-2002). Positive responses were observed in 5.9% of patch-tested subjects, with a significantly higher frequency in boys than in girls. The dermatitis was localized mainly on the face, hands and limbs. A significant linear increase in the annual frequency of propolis allergy was noted. Confirming literature data, a significant association with balsam of Peru sensitivity was present in children reacting to propolis, linked to the presence of common constituents in the 2 substances. In conclusion, based on our data, we suggest that propolis should not be used in topical products for children because of its high sensitization rate at the paediatric age.

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AllergensBalsamsChildChild, PreschoolDermatitis, Allergic ContactDermatitis, AtopicFacial DermatosesFemaleHand DermatosesHumansInfantItalyLeg DermatosesMalePatch TestsPropolisSex FactorsUpper ExtremityJournal Article

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Francesca Giusti, Roberta Miglietta, Patrizia Pepe, Stefania Seidenari. Sensitization to propolis in 1255 children undergoing patch testing.. https://doi.org/10.1111/j.0105-1873.2004.00455.x

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