Pathbase: a new reference resource and database for laboratory mouse pathology.

Paul N Schofield; Jonathan B L Bard; Jacques Boniver; Vincenzo Covelli; Philippe Delvenne; Michele Ellender; Wilhelm Engstrom; Wolfgang Goessner; Michael Gruenberger; Heinz Hoefler; John W Hopewell; Mariateresa Mancuso; Carmel Mothersill; Leticia Quintanilla-Martinez; Bjorn Rozell; Hannu Sariola; John P Sundberg; Andrew Ward

doi:10.1093/rpd/nch101

PubMed · 15623888

Pathbase: a new reference resource and database for laboratory mouse pathology.

Paul N Schofield·Jonathan B L Bard·Jacques Boniver·Vincenzo Covelli·Philippe Delvenne·Michele Ellender·Wilhelm Engstrom·Wolfgang Goessner·Michael Gruenberger·Heinz Hoefler·John W Hopewell·Mariateresa Mancuso·Carmel Mothersill·Leticia Quintanilla-Martinez·Bjorn Rozell·Hannu Sariola·John P Sundberg·Andrew Ward

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Abstract

Pathbase (http://www.pathbase.net) is a web accessible database of histopathological images of laboratory mice, developed as a resource for the coding and archiving of data derived from the analysis of mutant or genetically engineered mice and their background strains. The metadata for the images, which allows retrieval and interoperability with other databases, is derived from a series of orthogonal ontologies and controlled vocabularies. One of these controlled vocabularies, MPATH, was developed by the Pathbase Consortium as a formal description of the content of mouse histopathological images. The database currently has over 1000 images on-line with 2000 more under curation and presents a paradigm for the development of future databases dedicated to aspects of experimental biology.

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Animals Computational Biology Databases, Factual Genotype Information Storage and Retrieval Internet Mice Mutation Pathology Phenotype Vocabulary, Controlled Journal Article Research Support, Non-U.S. Gov't

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Paul N Schofield, Jonathan B L Bard, Jacques Boniver, Vincenzo Covelli, Philippe Delvenne, Michele Ellender, Wilhelm Engstrom, Wolfgang Goessner, Michael Gruenberger, Heinz Hoefler, John W Hopewell, Mariateresa Mancuso, Carmel Mothersill, Leticia Quintanilla-Martinez, Bjorn Rozell, Hannu Sariola, John P Sundberg, Andrew Ward. 2004. Pathbase: a new reference resource and database for laboratory mouse pathology.. https://doi.org/10.1093/rpd%2Fnch101

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