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PubMed · 15770816

[Inflammatory bowel diseases].

C Felley·J Guyot·J Hess·C Mottet·J Delarive·P Michetti
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Abstract

COX-2 specific anti-inflammatory agents appear as able to induce a flare of inflammatory bowel disease as classical anti-inflammatory agents. The use of steroids, immunomodulators or infliximab prior to surgery does not appear to increase post-operative complication rates. Cases of hepatitis B reactivation have been described after infliximab therapy, suggesting that hepatitis B serological status should be verified prior to infliximab therapy. Adalimubab, a fully humanized antibody directed against TNF-alpha, is efficacious in patients that have lost response or did not tolerate infliximab. Approval of this agent is still awaited. Leucoapheresis is a promising tool in ulcerative colitis.

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HumansImmunologic FactorsImmunosuppressive AgentsInflammatory Bowel DiseasesTumor Necrosis Factor-alphaEnglish AbstractJournal ArticleReview

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C Felley, J Guyot, J Hess, C Mottet, J Delarive, P Michetti. 2005-01-19. [Inflammatory bowel diseases].. https://pubmed.ncbi.nlm.nih.gov/15770816/

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