Salmonella typhimurium enterotoxin mediated fluid secretion.

S Khurana; N K Ganguly; D Panigrahi; M Khullar; B N Walia

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PubMed · 1577513

Salmonella typhimurium enterotoxin mediated fluid secretion.

S Khurana·N K Ganguly·D Panigrahi·M Khullar·B N Walia

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Abstract

Unidirectional Na+ and Cl- fluxes were studied in rats treated with S. typhimurium enterotoxin (S-LT). There was net absorption of Na+ and Cl- in the control group, while in the toxin treated animals there was net secretion of Na+ and Cl- (P less than 0.001). There was no change in the transport of D-glucose in the toxin treated group as compared to the control animals. The Na+, K(+)-ATPase pump was unaltered in the S-LT treated animals (198.67 +/- 11.23 nmoles Pi/mg protein/min) as compared to the control group (189.93 +/- 10.09 nmoles Pi/mg protein/min). There was no change in the unidirectional fluxes of Ca+2 in the S-LT treated animals as compared to the control animals, suggesting no change in the permeability of the S-LT treated intestinal membrane to Ca+2.

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Animals Bacterial Toxins Calcium Chlorides Endotoxins Enterotoxins Intestinal Mucosa Intestines Male Rats Rats, Inbred Strains Salmonella typhimurium Sodium Water-Electrolyte Balance Journal Article Research Support, Non-U.S. Gov't

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S Khurana, N K Ganguly, D Panigrahi, M Khullar, B N Walia. 1992. Salmonella typhimurium enterotoxin mediated fluid secretion.. https://pubmed.ncbi.nlm.nih.gov/1577513/

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