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PubMed · 15775658

[Effect of extracellular Ca2+ on neuronal function].

T Miyashita·H Abe·Y Kubo
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Abstract

Metabotropic glutamate receptors (mGluR) are well known to have a significance for the plastic change of synaptic neurotransmission. We observed that mGluR can be activated not only by glutamate but also by extracellular Ca(2+) of physiological concentration. Our observation suggests that extracellular Ca(2+) plays a critical role for the neuronal function, not only by serving as a source to elevate intracellular Ca(2+) concentration by entering through various channels, but also by activating metabotropic glutamate receptors as a ligand.

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T Miyashita, H Abe, Y Kubo. 2001. [Effect of extracellular Ca2+ on neuronal function].. https://pubmed.ncbi.nlm.nih.gov/15775658/

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