San1p, checking up on nuclear proteins.

Thomas Sommer; Christian Hirsch

doi:10.1016/j.cell.2005.03.003

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San1p, checking up on nuclear proteins.

Thomas Sommer·Christian Hirsch

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Abstract

Cellular quality control mechanisms perform vital tasks by ensuring that the proteome reflects precisely the information encoded by the genome. In this issue of Cell, Gardner et al. (2005) report the discovery of a novel protein quality control system that resides in the nucleus. Central to this system is the E3 ligase San1p, which monitors nuclear proteins and targets aberrant species for destruction.

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Cell Nucleus Genome Mutation Nuclear Proteins Proteome Saccharomyces cerevisiae Saccharomyces cerevisiae Proteins Signal Transduction Ubiquitin-Protein Ligases Journal Article Comment

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Thomas Sommer, Christian Hirsch. 2005-03-25. San1p, checking up on nuclear proteins.. https://doi.org/10.1016/j.cell.2005.03.003

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