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PubMed · 15804308

Generalized lichen nitidus.

Nawaf Al-Mutairi·Ayman Hassanein·Osama Nour-Eldin·Joshi Arun
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Abstract

Lichen nitidus is a rare chronic condition of unknown etiology. Generalized lichen nitidus is even rarer. We report here a 5-year-old girl who had multiple, asymptomatic, discrete, 1 to 2 mm flesh-colored, shiny, flat, papules on her face, upper limbs, and thighs with relative sparing of the trunk. Resolution of these papular lesions was followed by hyperpigmented macules in those areas. Histopathologic examination of a papular lesion revealed a localized granulomatous lymphohistiocytic infiltrate in an expanded dermal papilla with thinning of overlying epidermis and downward extension of the rete ridges at the lateral margin of the infiltrate, producing a typical "claw clutching a ball" picture, confirming our clinical diagnosis of lichen nitidus. The pigmented macules showed melanin pigmentation on histology. There was no response to oral astemizole treatment for 3 months. However, the lichen nitidus lesions resolved spontaneously without any further treatment over the next year, leaving behind a prominent pigmentary disturbance.

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AstemizoleChild, PreschoolFemaleHistamine H1 AntagonistsHumansLichen NitidusSkinTreatment OutcomeCase ReportsJournal Article

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BibTeXRIS

Nawaf Al-Mutairi, Ayman Hassanein, Osama Nour-Eldin, Joshi Arun. Generalized lichen nitidus.. https://doi.org/10.1111/j.1525-1470.2005.22215.x

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