Microtubule tips redirect actin assembly.

Anthony Bretscher

doi:10.1016/j.devcel.2005.03.008

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Microtubule tips redirect actin assembly.

Anthony Bretscher

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Abstract

In fission yeast, a protein complex that rides on the plus end of growing microtubules regulates establishment of new sites of actin cable assembly, necessary for cell growth, from one to both ends of the rod-shaped cells. Martin et al. describe a direct molecular link between the microtubule tip complex and the formin for3p, the nucleator for assembly of actin cables, which is necessary for this regulatory switch.

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Actins Cell Cycle Proteins Cytoskeleton Formins Microtubules Schizosaccharomyces Schizosaccharomyces pombe Proteins Journal Article Comment

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Anthony Bretscher. 2005. Microtubule tips redirect actin assembly.. https://doi.org/10.1016/j.devcel.2005.03.008

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