PubMed · 15916552
Systems biology: will it work?
Abstract
Systems biology describes the collection of a set of measurements on a system, integrated with a mathematical model of that system. The model and the measurements must be made together and refined iteratively, requiring close collaboration between biologists and modellers. A complete cell is probably too large and complicated to model yet, but simplified subsystems will probably produce valuable results. I consider various ways of simplifying the system and conclude that the biggest challenge is to get everyone working together productively.
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M P Williamson. 2005. Systems biology: will it work?. https://doi.org/10.1042/bst0330503
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