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The regional rule for bacterial base composition.

Graeme Mitchison
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Abstract

If one looks at the composition of coding DNA and of three types of intergenic regions--those between convergent, parallel and divergent genes--a striking pattern is seen in a wide range of bacteria. The AT-content of coding sequence is lowest, and the AT-contents of the intergenic regions increase in the order: convergent, parallel and divergent. Why does this pattern occur? In this article, I suggest an explanation based on the structural requirements for the binding of transcription factors.

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BacteriaBacterial ProteinsBase CompositionBinding SitesDNA, BacterialEscherichia coliGenome, BacterialModels, GeneticNucleic Acid ConformationThermodynamicsTranscription FactorsJournal Article

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Graeme Mitchison. 2005. The regional rule for bacterial base composition.. https://doi.org/10.1016/j.tig.2005.06.002

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