Stroboscopic ultrahigh-resolution full-field optical coherence tomography.

G Moneron; A C Boccara; A Dubois

doi:10.1364/ol.30.001351

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PubMed · 15981530

Stroboscopic ultrahigh-resolution full-field optical coherence tomography.

G Moneron·A C Boccara·A Dubois

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Abstract

We present a new technique that produces en face tomographic images with a 10-micros acquisition time per image. The setup consists of an interference microscope with stroboscopic illumination provided by a xenon arc flash lamp (10-micros flashes at 15 Hz). The tomographic images are obtained from two phase-opposed interferometric images recorded simultaneously by two synchronized CCD cameras. Transverse resolution better than 1.0 microm is achieved by use of high-numerical-aperture microscope objectives. The short coherence length of the source yields an axial resolution of 0.9 microm. 3 x 3 pixel binning leads to a detection sensitivity of 71 dB. Our system is suitable for various applications, particularly in biology for in vivo cellular-level imaging.

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Animals Equipment Design Equipment Failure Analysis Eye Image Enhancement Microscopy, Interference Signal Processing, Computer-Assisted Stroboscopy Tomography, Optical Coherence Xenopus laevis Evaluation Study Journal Article Research Support, Non-U.S. Gov't

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G Moneron, A C Boccara, A Dubois. 2005-06-01. Stroboscopic ultrahigh-resolution full-field optical coherence tomography.. https://doi.org/10.1364/ol.30.001351

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