PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 16007325

[Upper cervical chondrosarcoma].

C J Domínguez·S Martín-Ferrer·J Rimbau·C Joly
View original source ↗Export metadata ↓

Abstract

Spinal chondrosarcoma are extremely rare and slowly growing tumors. They have been reported in thoraco-lumbar spine and lower cervical spine. Our case, a female, has a tumor located in the axis with extension into C3 and then caudally to C4 as the disease progressed. We present a technical innovation in spinal stabilization and compare our result with previously reported cases.

Explore related subjects

Antineoplastic Combined Chemotherapy ProtocolsAxis, Cervical VertebraBrachytherapyCervical VertebraeChondrosarcomaDisease ProgressionDoxorubicinFemaleHumansIfosfamideInternal FixatorsLymphatic MetastasisMiddle AgedNeoplasm Recurrence, LocalSpinal NeoplasmsTomography, X-Ray ComputedTreatment FailureCase ReportsEnglish AbstractJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

C J Domínguez, S Martín-Ferrer, J Rimbau, C Joly. 2005. [Upper cervical chondrosarcoma].. https://pubmed.ncbi.nlm.nih.gov/16007325/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2008

Treatment of metastatic sialoblastoma with chemotherapy and surgery.

Tumors of the salivary gland are very uncommon in children. Sialoblastoma is a rare, aggressive, blastomatous, and potentially malignant congenital tumor. Distant metastases are rare. We present a case of sialoblastoma with lung metastases that developed in a 4-year-old girl adjacent to a congenital nevus in the left cheek. The tumor was inoperable at diagnosis but the largest of the pulmonary metastases was removed surgically. The patient responded well to chemotherapy and underwent surgical excision of the primary tumor, followed by three more courses of chemotherapy.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed2008

Long-term remission of children with relapsed and secondary anaplastic large cell non-Hodgkin lymphoma (ALCL) following treatment with pulsed dexamethasone and low dose etoposide.

Anaplastic large cell lymphoma (ALCL) accounts for approximately 15% of childhood NHL. Relapsed ALCL represents a formidable challenge because outcome is poor despite the use of high-dose chemotherapy regimens. We report two patients with relapsed T-type and 0-type ALCL who achieved long-term 3rd and 4th remissions with 4-weekly oral dexamethasone (DEX) and etoposide pulses for 2 years. This regimen also induced and maintained remission in a third patient with Nijmegen breakage syndrome (NBS) with secondary T-type ALCL. These patients demonstrate that low-intensity oral chemotherapy can induce long-term remissions and offer a curative perspective in refractory, relapsed and secondary ALCL.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed2007

Therapy-related acute myeloid leukemia in a child with Noonan syndrome and clonal duplication of the germline PTPN11 mutation.

A 4-year-old girl with Noonan syndrome (NS) and constitutive PTPN11 mutation presented with stage 4 neuroblastoma and was treated by intensive chemotherapy. During the treatment, cytogenetic analysis revealed the development of a hyperdiploid clone with duplication of the germline PTPN11 mutation in a morphologically normal bone marrow. A few months later, the patient developed acute myelomonoblastic leukemia with an additional clonal deletion of 7q. Although, we cannot conclude whether there is an association between NS and neuroblastoma, this case suggests that duplication of germline PTPN11 mutations, potentially induced by chemotherapy, contributes to leukemogenesis in patients with NS.

Antineoplastic Combined Chemotherapy Protocols↗