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Energizer: PGC-1 alpha keeps the heart going.

Motoaki Sano·Michael D Schneider
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Abstract

In the current issue of Cell Metabolism, Arany et al. (2005) demonstrate essential roles for PGC-1alpha in cardiac metabolism, proving several long-postulated functions while disproving others. These experiments conclusively reinforce the logic of rescuing PGC-1alpha as a novel therapeutic target in heart failure.

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AnimalsHeart FailureMiceMyocardiumPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaTrans-ActivatorsTranscription FactorsJournal ArticleComment

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Motoaki Sano, Michael D Schneider. 2005. Energizer: PGC-1 alpha keeps the heart going.. https://doi.org/10.1016/j.cmet.2005.03.009

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