Salmonella's sensor for host defense molecules.

Robert E W Hancock; Joseph B McPhee

doi:10.1016/j.cell.2005.07.023

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Salmonella's sensor for host defense molecules.

Robert E W Hancock·Joseph B McPhee

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Abstract

The bacterial pathogen Salmonella typhimurium resides within phagosomes in host cells and is able to deflect the host immune response. In this issue of Cell, Bader et al. (2005) decipher an elegant mechanism by which the PhoQ sensor kinase of Salmonella is switched on by host cationic antimicrobial peptides, leading to changes in gene expression that enable Salmonella to combat the host immune response.

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Antimicrobial Cationic Peptides Bacterial Proteins Gene Expression Regulation, Bacterial Host-Parasite Interactions Humans Protein Kinases Salmonella typhimurium Comment Journal Article Review

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Robert E W Hancock, Joseph B McPhee. 2005-08-12. Salmonella's sensor for host defense molecules.. https://doi.org/10.1016/j.cell.2005.07.023

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