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PubMed · 16187708

[Ventilator associated acute lung injury].

Silvio Antonio Namendys-Silva·Juan Gabriel Posadas-Calleja
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Abstract

Mechanical ventilation plays a central role in the critical care setting; but its use is closely related with some life threatening complications as nosocomial pneumonia and low cardiac performance. One of the most severe complications is called ventilator-associated lung injury (VALI) and it includes: Barotrauma, volutrauma, atelectrauma, biotrauma and oxygen-mediated toxic effects and it is related with an inflammatory response secondary to the stretching and recruitment process of alveoli within mechanical ventilation. The use of some protective ventilatory strategies has lowered the mortality rate 10% approximately.

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Acute DiseaseAirway ResistanceAnimalsBarotraumaClinical Trials as TopicDilatation, PathologicElasticityHemodynamicsHumansLung InjuryOxidative StressOxygenOxygen Inhalation TherapyPositive-Pressure RespirationPressurePulmonary AlveoliPulmonary EdemaRatsRespiration, ArtificialStress, MechanicalEnglish AbstractJournal ArticleReview

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Silvio Antonio Namendys-Silva, Juan Gabriel Posadas-Calleja. [Ventilator associated acute lung injury].. https://pubmed.ncbi.nlm.nih.gov/16187708/

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