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PubMed · 16223177

[A case of cervical endodermal cyst].

Noboru Kusaka·Tomoko Maruo·Mitsuhisa Nishiguchi·Kazuhiro Takayama·Yasuhiko Maeda·Kotaro Ogihara·Masaki Gotoh·Tsukasa Nishiura·Ichiro Murakami
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Abstract

A very rare case involving an endodermal cyst of the cervical spinal canal was documented. In 1999, a 28-year-old male presented with mild tetraplegia due to a traffic accident and consequently, he was admitted to another hospital. Magnetic resonance imaging (MRI) performed at that time demonstrated a cervical cord cyst. He was treated conservatively and as a result, complete resolution of symptoms was achieved. Five years later, he presented with progressive right hemiparesis and was referred to our institute. MRI at the time of admission exhibited an intradural extramedullary cystic lesion on the ventral side of the spinal cord at the C5-6 levels, which was characterized by low intensity on T1-weighted, and by high intensity on T2-weighted images. The cyst, which had increased in size, compressed the spinal cord remarkably backward. The anterior central vertebrectomy approach was performed. Subtotal resection of the cyst wall was conducted due to its tight partical adhesion to the spinal cord. The vertebral defect was reconstructed with an autogenous iliac graft. According to histological findings the cyst wall consisted of a single layer of columnar epithelial cells with secretory granules and immunohistochemical examination revealed that the cyst wall was positive for cytokeratin 7. Symptoms improved immediately. Subsequently, the patient was discharged with good performance status. Endodermal cysts are very rare developmental cysts derived from the embryonic endodermal layer. Moreover, these lesions are usually located intradurally in the cervical and upper dorsal spine ventral to the spinal cord. Total removal of the cyst is recommended if it is possible. However, total resection is often difficult due to adhesion of the cyst wall to the neural tissue so invasive resection should be avoided. In such cases, follow-up MRI is necessary in order to exclude recurrence of the remnant lesion.

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AdultBiomarkersCentral Nervous System CystsCervical VertebraeDiagnosis, DifferentialEndodermHumansKeratin-7KeratinsLaminectomyMagnetic Resonance ImagingMaleCase ReportsEnglish AbstractJournal Article

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Noboru Kusaka, Tomoko Maruo, Mitsuhisa Nishiguchi, Kazuhiro Takayama, Yasuhiko Maeda, Kotaro Ogihara, Masaki Gotoh, Tsukasa Nishiura, Ichiro Murakami. 2005. [A case of cervical endodermal cyst].. https://pubmed.ncbi.nlm.nih.gov/16223177/

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