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PubMed · 16229242

[Adhesion molecules in type 2 diabetes].

Alina Sokup
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Abstract

Abnormal levels some of serum soluble adhesion molecules (ICAM-1, VICAM-1, E-selectin, P-selectin, L-selectin) have been detected in type 2 diabetic patients. There is some evidence that levels of soluble adhesion molecules depend on glycemic control, disturbances of lipid metabolism, obesity and insulin resistance. There is a few of clinical data till now, which have been suggested the significance role of adhesion molecules in pathogenesis of microangiopathy and macroangiopathy in type 2 diabetics. It is possible that in some cases measurement of serum adhesion molecules may be useful for predicting, early diagnosing prophylactic and monitoring of treatment of diabetic type 2 complications. We can modify serum levels of soluble adhesion molecules by nonpharmacologic and pharmacologic treatment.

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Cell Adhesion MoleculesDiabetes ComplicationsDiabetes Mellitus, Type 2Diabetic AngiopathiesHumansIntercellular Adhesion Molecule-1Risk FactorsSelectinsVascular Cell Adhesion Molecule-1English AbstractJournal ArticleReview

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Alina Sokup. 2005. [Adhesion molecules in type 2 diabetes].. https://pubmed.ncbi.nlm.nih.gov/16229242/

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