Bacterial location in chronic sinusitis.

Anders Ebenfelt

PubMed · 16270599

Bacterial location in chronic sinusitis.

Abstract

BACKGROUND: In chronic nonallergic sinusitis, it is often assumed that bacteria invade the sinus mucosa where the inflammatory condition begins and is maintained. However, the bacterial presence in a normal or moderately damaged epithelial layer has never been proved in biopsy studies. METHODS: In this study, mucosal samples from six consecutive patients with chronic sinusitis were examined. Transmission electron microscopy was used and the presence of bacterial invasion and formation of phagosomes containing bacteria as a marker of host response were studied. RESULTS: Phagocytosis of bacteria was observed in the sinus mucosa in samples from only one patient. In the other five patients, no signs of phagocytosis were seen. CONCLUSION: Based on these results, we concluded that in chronic sinusitis, bacterial invasion in sinus mucosa is not an obligatory phenomenon.

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Bacteria Bacterial Adhesion Chronic Disease Humans Maxillary Sinus Maxillary Sinusitis Microscopy, Electron, Transmission Mucous Membrane Neutrophils Phagosomes Journal Article

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Anders Ebenfelt. Bacterial location in chronic sinusitis.. https://pubmed.ncbi.nlm.nih.gov/16270599/

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