PubMed · 16293856
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O Noel Gill, Catherine M Lowndes. 2005-11-19. Data are still needed for HPV immunisation programme.. https://doi.org/10.1136/bmj.331.7526.1204-b
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Military command and control (C2) organizations are complex socio-technical systems which must constantly adapt to meet changing operational requirements. We describe our experiences in developing a work-centred support system (WCSS) to aid weather forecasting and monitoring in a military airlift C2 organization as an illustrative case. As part of the development process we conducted field observations both before and after introduction of the WCSS in their operations centre. A striking finding was the constant changes that operations personnel faced (changes in goals and priorities, changes in scale of operations, changes in team roles and structure, and changes in information sources and systems). We describe the changes in workplace demands that we observed and the modifications we needed to make to the WCSS in response. For today's fielded systems, it is seldom possible to make changes that are responsive to users' changing requirements in a timely manner. We argue for the need to incorporate facilities that enable users to adapt their systems to the changing requirements of work and point to some promising directions towards evolvable work-centred support systems.
Twins are a valuable resource not only for studies on multiple births themselves, but on the etiology of diseases and other phenotypes. The method of ascertainment and selection of twins can be crucial for such studies and population based twin registries are thus of great importance as tools of research. Accurate determination of zygosity and chorionicity is essential in all studies of multiple births and in their professional care. The parents and the multiples ask for it. It is of pre-and postnatal medical importance and now considered as a prerequisite in several domains of twin research. It is also important for educational reasons as it helps the multiples and their parents and teachers to ascertain identity. The methods are briefly described and a plea is made to the obstetricians and pediatricians to use them systematically at birth. The distribution of zygosity and chorionicity types among spontaneous and induced twin births are illustrated.
BACKGROUND: While information about 4 million neonatal deaths worldwide is limited, even less information is available for stillbirths (babies born dead in the last 12 weeks of pregnancy) and there are no published, systematic global estimates. We sought to identify available data and use these to estimate the rates and numbers of stillbirths for 190 countries for the year 2000, and provide uncertainty estimates. METHODS: We assessed three sources of stillbirth data according to specified inclusion criteria: vital registration; demographic and health surveys (DHS), based on a new analysis of contraceptive calendar data; and study reports that include published studies identified through systematic literature searches of more than 30,000 abstracts and unpublished studies. A random effects regression model was developed to predict national stillbirth rates and associated uncertainty intervals. FINDINGS: Data from 44 countries with vital registration (71,442 stillbirths), 30 DHS surveys from 16 countries (2989 stillbirths), and 249 study populations from 103 countries (93,023 stillbirths) met the inclusion criteria. Model-based estimates were used for 128 countries. For 62 countries, the observed values were adjusted by a correction factor derived from the model. The resultant stillbirth rates ranged from five per 1000 in rich countries to 32 per 1000 in south Asia and sub-Saharan Africa. The estimated number of global stillbirths is 3.2 million (uncertainty range 2.5-4.1 million). In light of the data limitations and the conservative approach taken, the real number might be higher than this. INTERPRETATION: The numbers of stillbirths are high and there is a dearth of usable data in countries and regions in which most stillbirths occur, with under-reporting being a major challenge. Although our estimates are probably underestimates, they represent a rigorous attempt to measure the numbers of babies dying during the last trimester of pregnancy. Improving stillbirth data is the first step towards making stillbirths count in public-health action.