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Experimental autoimmune uveoretinitis (EAU) versus experimental allergic encephalomyelitis (EAE): a comparison of T cell-mediated mechanisms.

V L Calder·S L Lightman
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Abstract

EAU is a model of ocular inflammatory disease. EAU resembles another T cell-mediated autoimmune disease--experimental allergic encephalomyelitis--since both have increased expression of MHC class II molecules in the target tissue, can be adoptively transferred by activated CD4+ T cells and are inhibited by cyclosporin A. The immunological findings will be compared to find out if the same cellular mechanisms are involved in both diseases.

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AnimalsAutoimmune DiseasesBlood-Brain BarrierEncephalomyelitis, Autoimmune, ExperimentalImmunotherapyRetinitisT-LymphocytesUveitisComparative StudyJournal ArticleReview

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V L Calder, S L Lightman. 1992. Experimental autoimmune uveoretinitis (EAU) versus experimental allergic encephalomyelitis (EAE): a comparison of T cell-mediated mechanisms.. https://doi.org/10.1111/j.1365-2249.1992.tb06926.x

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