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Oculomotor nerve palsy evaluated by diffusion-tensor tractography.

Kei Yamada·Kensuke Shiga·Osamu Kizu·Hirotoshi Ito·Katsuhisa Akiyama·Masanori Nakagawa·Tsunehiko Nishimura
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Abstract

INTRODUCTION: The aim of the study was to test the feasibility of the tractography technique based on diffusion-tensor imaging (DTI) for the assessment of small infarcts involving the brainstem. METHODS: A patient who presented with an isolated left third cranial nerve palsy underwent magnetic resonance examination. Images were obtained by use of a whole-body, 1.5-T imager. Data were transferred to an off-line workstation for fiber tracking. RESULTS: The conventional diffusion-weighted imaging (DWI) performed using a 5 mm slice thickness could only depict an equivocal hyperintensity lesion located at the left paramedian midbrain. An additional thin-slice DTI was performed immediately after the initial DWI using a 3 mm slice thickness and was able to delineate the lesion more clearly. Image postprocessing of thin-slice DTI data revealed that the lesion location involved the course of the third cranial nerve tract, corresponding with the patient's clinical symptoms. CONCLUSION: The tractography technique can be applied to assess fine neuronal structures of the brainstem, enabling direct clinicoradiological correlation of small infarcts involving this region.

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AgedAnisotropyDiffusion Magnetic Resonance ImagingHumansMaleOculomotor Nerve DiseasesCase ReportsJournal Article

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Kei Yamada, Kensuke Shiga, Osamu Kizu, Hirotoshi Ito, Katsuhisa Akiyama, Masanori Nakagawa, Tsunehiko Nishimura. 2006-03-15. Oculomotor nerve palsy evaluated by diffusion-tensor tractography.. https://doi.org/10.1007/s00234-006-0070-7

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