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Iterferon induction in mice by BHK cells persistently infected with HVJ.

Y Ito·Y Nisiyama·K Shimokata·Y Kimura·I Nagata
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Abstract

Intraperitoneal injection into mice of BHK-HVJ cells (BHK cells persistently infected with HVJ) induced considerable amounts of circulating interferon. Sonication of BHK-HVJ cells almost totally abolished their interferon inducing capacities. This result suggests that a certain native organized structure of virus infected cells might be essential for production of interferon in this system, as is suggested in the in vitro sytem.

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AnimalsCell LineCells, CulturedCricetinaeInjections, IntraperitonealInterferonsKidneyMiceMice, Inbred C57BLParainfluenza Virus 1, HumanSonicationTransplantation, HeterologousComparative StudyJournal Article

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Y Ito, Y Nisiyama, K Shimokata, Y Kimura, I Nagata. 1975. Iterferon induction in mice by BHK cells persistently infected with HVJ.. https://doi.org/10.1099/0022-1317-27-1-93

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