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PubMed · 1683578

Piperacillin compared with cefuroxime plus metronidazole in diffuse peritonitis.

M Paakkonen·E M Alhava·R Huttunen·K Karjalainen·J Lahtinen·P Miettinen·H Silvola·J Viitanen
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Abstract

Eighty-five patients were randomly allocated to receive either piperacillin (n = 38) or cefuroxime plus metronidazole (n = 45) after surgical treatment of diffuse peritonitis; 78 were evaluable. A mean of 1.5 (piperacillin group) and 1.7 (cefuroxime/metronidazole group) pathogens/patient were identified. Twenty-seven patients (71%) were successfully treated in the piperacillin group compared with 29 (64%) in the cefuroxime/metronidazole group. These data suggest that piperacillin was neither better nor worse than cefuroxime/metronidazole in diffuse, secondary peritonitis.

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Acute DiseaseAdolescentAdultAgedAged, 80 and overCefuroximeDrug Therapy, CombinationFemaleHumansMaleMetronidazoleMiddle AgedPeritonitisPiperacillinClinical TrialComparative StudyJournal ArticleRandomized Controlled Trial

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M Paakkonen, E M Alhava, R Huttunen, K Karjalainen, J Lahtinen, P Miettinen, H Silvola, J Viitanen. 1991. Piperacillin compared with cefuroxime plus metronidazole in diffuse peritonitis.. https://pubmed.ncbi.nlm.nih.gov/1683578/

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