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Plenty new under the sun.

Jonathan Rees
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Abstract

Variation at the melanocortin 1 receptor (MC1R) is very common in most non-African world populations. A range of variants predispose to skin cancer, including melanoma. What remains unclear are the mechanisms linking gene variation with sun sensitivity or tumor risk. In particular, it remains unclear whether pigmentary effects of the MC1R can account for all of the increase in cancer risk.

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HumansMelanomaReceptor, Melanocortin, Type 1Risk FactorsSkin NeoplasmsSkin PigmentationCommentJournal ArticleReview

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Jonathan Rees. 2006. Plenty new under the sun.. https://doi.org/10.1038/sj.jid.5700345

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