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Animal evolution: when did the 'Hox system' arise?

Chris T Amemiya·Günter P Wagner
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Abstract

The origins of the Hox gene clusters and their coordinated activities during development have long been of considerable interest to biologists. In a recent paper in Current Biology, the Hox-like genes of two cnidarians are interpreted as evidence that the 'Hox system', sensu stricto, originated after the split from the lineage leading to bilaterian animals and that it was not requisite for complex axial patterning.

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AnimalsEvolution, MolecularHomeodomain ProteinsMultigene FamilyPhylogenyProtein Structure, TertiaryScyphozoaSea AnemonesCommentJournal Article

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Chris T Amemiya, Günter P Wagner. 2006-07-25. Animal evolution: when did the 'Hox system' arise?. https://doi.org/10.1016/j.cub.2006.06.051

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