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Nimbolide and isonimbolide.

G Anitha·J Josepha Lourdu Raj·S Narasimhan·K Anand Solomon·S S Rajan
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Abstract

Nimbolide 1, a potent molecule of biological significance, was isolated. Attempts were made to cleave the ether linkage in nimbolide using boron trifluoride etherate in the presence of tetrabutyl ammonium bromide so as to generate a ring-opened structure akin to azadirachtins, which are known to possess excellent antifeedant properties. However, a novel rearranged product was envisaged during the course of the reaction, which was determined as isonimbolide 2-a structural isomer of nimbolide through spectroscopic methods.

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G Anitha, J Josepha Lourdu Raj, S Narasimhan, K Anand Solomon, S S Rajan. Nimbolide and isonimbolide.. https://doi.org/10.1080/10286020500173267

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