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ZOning out tight junctions.

Kunyoo Shin·Ben Margolis
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Abstract

The tight junction is an intricate seal between adjoining epithelial cells that also separates the apical and basolateral membranes within these cells. A paper in this issue of Cell by Umeda et al. (2006) demonstrates that loss of the ZO scaffolding proteins prevents the formation of tight junctions but surprisingly does not perturb apico-basal polarity.

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AnimalsCell PolarityEpithelial CellsMembrane ProteinsMicePhosphoproteinsProtein IsoformsRNA, Small InterferingTight JunctionsZonula Occludens-1 ProteinCommentJournal Article

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Kunyoo Shin, Ben Margolis. 2006-08-25. ZOning out tight junctions.. https://doi.org/10.1016/j.cell.2006.08.005

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