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Diabetes-induced decrease in renal oxygen tension: effects of an altered metabolism.

Fredrik Palm·Per-Ola Carlsson·Angelica Fasching·Peter Hansell·Per Liss
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Abstract

During conditions with experimental diabetes mellitus, it is evident that several alterations in renal oxygen metabolism occur, including increased mitochondrial respiration and increased lactate accumulation in the renal tissue. Consequently, these alterations will contribute to decrease the interstitial pO2, preferentially in the renal medulla of animals with sustained long-term hyperglycemia.

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AnimalsDiabetes Mellitus, ExperimentalDiabetic NephropathiesHumansKidneyOxygen ConsumptionJournal ArticleResearch Support, Non-U.S. Gov'tReview

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Fredrik Palm, Per-Ola Carlsson, Angelica Fasching, Peter Hansell, Per Liss. 2006. Diabetes-induced decrease in renal oxygen tension: effects of an altered metabolism.. https://doi.org/10.1007/0-387-29540-2_26

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