Vascular tumor targeting.

J Ahlskog; G Paganelli; D Neri

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PubMed · 17043627

Vascular tumor targeting.

J Ahlskog·G Paganelli·D Neri

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Abstract

The growth of solid tumors is dependent on their capacity to acquire blood supply. Therefore, much effort has been directed towards the development of anti-angiogenic agents which inhibit the process of neovascularization. More recently, it has become apparent that the targeted destruction of the established tumor vasculature represents a complementary avenue for growing therapeutic opportunities. This review provides evidence that vascular tumor targeting is an effective anti-tumor strategy in animal models. It further describes strategies for the identification of putative tumor vascular targets and discusses future prospects for vascular targeting applications in the clinical setting.

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Drug Delivery Systems Humans Neoplasms Neovascularization, Pathologic Radioisotopes Radiopharmaceuticals Journal Article Review

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J Ahlskog, G Paganelli, D Neri. 2006. Vascular tumor targeting.. https://pubmed.ncbi.nlm.nih.gov/17043627/

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