Exiting the outside world for cross-presentation.

Kenneth L Rock

doi:10.1016/j.immuni.2006.09.003

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Exiting the outside world for cross-presentation.

Kenneth L Rock

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Abstract

How are extracellular proteins cross-presented on MHC class I molecules? In this issue of Immunity, demonstrate that the ER-associated degradation (ERAD) export pathway operates in the phagosomes of dendritic cells and transfers antigens into the MHC class I pathway.

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Antigen Presentation Cross-Priming Dendritic Cells Endoplasmic Reticulum Histocompatibility Antigens Class I Humans Phagosomes Protein Transport Proteins Comment Journal Article

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Kenneth L Rock. 2006. Exiting the outside world for cross-presentation.. https://doi.org/10.1016/j.immuni.2006.09.003

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