Molecular signaling in feather morphogenesis.

Chih-Min Lin; Ting Xin Jiang; Randall B Widelitz; Cheng-Ming Chuong

doi:10.1016/j.ceb.2006.10.009

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PubMed · 17049829

Molecular signaling in feather morphogenesis.

Chih-Min Lin·Ting Xin Jiang·Randall B Widelitz·Cheng-Ming Chuong

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Abstract

The development and regeneration of feathers have gained much attention recently because of progress in the following areas. First, pattern formation. The exquisite spatial arrangement provides a simple model for decoding the rules of morphogenesis. Second, stem cell biology. In every molting, a few stem cells have to rebuild the entire epithelial organ, providing much to learn on how to regenerate an organ physiologically. Third, evolution and development ('Evo-Devo'). The discovery of feathered dinosaur fossils in China prompted enthusiastic inquiries about the origin and evolution of feathers. Progress has been made in elucidating feather morphogenesis in five successive phases: macro-patterning, micro-patterning, intra-bud morphogenesis, follicle morphogenesis and regenerative cycling.

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Animals Body Patterning Ectoderm Feathers Gene Expression Regulation, Developmental Genes, Homeobox Models, Biological Morphogenesis Regeneration Skin Journal Article Research Support, N.I.H., Extramural Review

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Chih-Min Lin, Ting Xin Jiang, Randall B Widelitz, Cheng-Ming Chuong. 2006-10-17. Molecular signaling in feather morphogenesis.. https://doi.org/10.1016/j.ceb.2006.10.009

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