PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 1705070

[Arachnoid cysts (pathomorphological studies)].

G F Dobrovol'skiĭ·T M Vikhert·N I Ivakina·L A Nikulina
View original source ↗Export metadata ↓

Abstract

Based on a macro- and microscopic analysis of the material of 2 section cases and 29 biopsies of persons operated on for arachnoidal cysts two types of cysts were distinguished: 1) arachnoidal cysts that occurred as a result of isolated congenital pathology of the leptomeninx; 2) cysts representing a manifestation of the combined developmental abnormality of the CNS occurring in the form of arachnoidal cysts coupled with intracerebral ones and with pathology of the adjacent cortical parts in the form of gross impairment of its architectonics and developmental abnormality of cerebral vessels.

Explore related subjects

ArachnoidArachnoid CystsChild, PreschoolFemaleHumansMaleMiddle AgedStaining and LabelingCase ReportsEnglish AbstractJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

G F Dobrovol'skiĭ, T M Vikhert, N I Ivakina, L A Nikulina. 1990. [Arachnoid cysts (pathomorphological studies)].. https://pubmed.ncbi.nlm.nih.gov/1705070/

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed1992

Immunohistochemical localization of cell adhesion molecule epithelial cadherin in human arachnoid villi and meningiomas.

Cadherins are a family of intercellular glycoproteins responsible for calcium-dependent cell adhesion and are currently divided into four types: epithelial (E), neuronal (N), placental (P), and vascular (V). Since cadherins are known to be indispensable for not only morphogenesis in the embryo but also maintenance of tumor cell nest, we examined the expression of E-cadherin in 31 meningiomas (11 syncytial, 12 transitional, 8 fibroblastic) and 3 arachnoid villi by immunoblot and immunohistochemical analyses. In the immunoblot analysis, E-cadherin was detected at the main band of Mr 124,000 in all of the arachnoid villi, as well as syncytial and transitional types of meningiomas, but not in the fibroblastic type. The immunohistochemical examination showed that E-cadherin was expressed at the cell borders of syncytial and transitional types, but the expression was absent in the fibroblastic type. Immunoelectron microscopy showed that E-cadherin was localized at the intermediate junctions in arachnoid villi, while it was detected diffusely at the cell surface in meningiomas. It is suggested from these data that the expression of E-cadherin might be closely related to the differentiation and organogenesis of meningioma cells.

Arachnoid↗