PubMed · 17072077
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K Vijayraghavan. 2006. Reading Waddington today.. https://doi.org/10.1007/bf02729014
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This paper is part of the ongoing efforts within the framework of the Open Biomedical Ontologies (OBO) ontology library to optimize the treatment of relations in biomedical informatics. When ovum and sperm fuse to form a zygote, then the latter is derived from the former. This derives_from relation is of huge importance not only in embryology but also in every other science dealing with ontogenetic processes. This study examines critically the treatment of derives_from in the OBO Relation Ontology in light of its conformity to the underlying processes of development and transformation in biological and medical reality.
As a result of the birth of Louise Brown, the Government, in 1982 set up the committee of Inquiry into Human Fertilisation and Embryology (The Warnock Committee). This committee made a number of recommendations including one that recommended the setting up of a body to regulate these procedures. The Medical Research Council and the Royal College of Obstetricians and Gynaecologists in the interim set up a voluntary body to regulate the centres doing IVF. This was called the Voluntary Licensing Authority (VLA) for Human in-vitro Fertilisation and Embryology. Centres were visited and licensed. This body regulated the centres until the statutory body the Human Fertilisation and Embryology Authority (HFEA) was formed in 1990.