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PubMed · 17150496

Formation of dendrimeric RNA assemblies though RNA loop-loop interactions.

Isamu Fujiya·Kazuo Harada
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Abstract

We describe the construction of nano-scale dendritic assemblies using RNA building blocks based on dimerization initiation site (DIS) RNA of the human immunodeficiency virus type 1 (HIV-1) that forms stable base pairing through loop-loop ("kissing") interactions. RNA building blocks containing three DIS-like hairpins connected by a two nucleotide linker self-assembled in a magnesium-dependent manner to form dendrimeric structures as observed by non-denaturing polyacrylamide gel electrophoresis (PAGE).

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Base SequenceDendrimersElectrophoresis, Polyacrylamide GelHIV-1HumansMolecular Sequence DataNucleic Acid ConformationRNA, ViralJournal Article

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Isamu Fujiya, Kazuo Harada. 2004. Formation of dendrimeric RNA assemblies though RNA loop-loop interactions.. https://doi.org/10.1093/nass%2F48.1.97

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