Suitability of the cingulate cortex for neural control.

Timothy C Marzullo; Charles R Miller; Daryl R Kipke

doi:10.1109/tnsre.2006.886730

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PubMed · 17190032

Suitability of the cingulate cortex for neural control.

Timothy C Marzullo·Charles R Miller·Daryl R Kipke

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Abstract

Recent neuroprosthetic work has focused on the motor cortex as a source of voluntary control signals. However, the motor cortex can be damaged in upper motor neuron degenerative diseases such as primary lateral sclerosis and amyotrophic lateral sclerosis. The possibility exists that prefrontal areas may also be used in neuroprosthetic devices. Here, we report the use of the cingulate cortex in a neuroprosthetic model. Seven rats were able to significantly modulate spiking activity in the cingulate cortex in order to receive reward. Furthermore, experiments with single neurons provide evidence that the cingulate cortex neuronal modulation is highly flexible and thus useful for a neuroprosthetic device.

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Action Potentials Animals Biofeedback, Psychology Cerebral Cortex Electroencephalography Evoked Potentials Gyrus Cinguli Neurons Rats Rats, Sprague-Dawley Volition Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

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Timothy C Marzullo, Charles R Miller, Daryl R Kipke. 2006. Suitability of the cingulate cortex for neural control.. https://doi.org/10.1109/tnsre.2006.886730

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