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Restricted diffusion in Canavan disease.

S G Srikanth·H S Chandrashekar·K Nagarajan·P N Jayakumar
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Abstract

INTRODUCTION: Canavan disease is a megalencephalic leukodystrophy due to deficiency of the enzyme aspartoacylase. Proton MR spectroscopy finding of elevated N-acetyl-L: -aspartate is considered diagnostic of Canavan disease. CASE REPORT: We report a case of Canavan disease, which showed restricted diffusion in diffusion-weighted imaging and discuss the cause of it.

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AmidohydrolasesAspartic AcidCanavan DiseaseDiffusion Magnetic Resonance ImagingHumansInfantMagnetic Resonance SpectroscopyMaleCase ReportsJournal Article

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S G Srikanth, H S Chandrashekar, K Nagarajan, P N Jayakumar. 2007-01-12. Restricted diffusion in Canavan disease.. https://doi.org/10.1007/s00381-006-0238-9

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