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PubMed · 1729922

A method for ensuring proper function of multiorifice catheters.

P J Donahue·P R Satwicz
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CatheterizationEquipment FailureHumansPulmonary ArteryCommentLetter

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P J Donahue, P R Satwicz. 1992. A method for ensuring proper function of multiorifice catheters.. https://doi.org/10.1097/00000542-199201000-00026

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Immune heparin-induced thrombocytopenia (HIT) is a life-threatening adverse effect of heparin. It can result from any type of heparin exposure and by any route of administration; however only a few cases are reported after exposures to small quantities of heparin from catheter flushes. The major clinical problem associated with HIT is thrombosis. Early detection and institution of alternative, non-heparin anticoagulation are important. We report a patient with HIT associated with use of therapeutic-dose unfractionated heparin in whom immune sensitization to heparin was triggered by two 500-unit exposure to UFH associated with intravascular catheter flushing for antineoplastic chemotherapy in a patient with colon adenocarcinoma.

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