PubMed Health⌕ Search
Home/Archive/PubMed

PubMed · 1910385

[Kimura disease--2 case reports].

H Hess·B Ströhmann·H Martin
View original source ↗Export metadata ↓

Abstract

Two histologically confirmed cases of Kimura's disease are reported in the present article. Emphasis is placed on the clinical symptoms in conjunction with the histological picture. Recent studies in the literature are discussed with respect to differential diagnosis, etiology and therapy. In all ENT-tumours of unknown origin this relatively uncommon disease should also be considered.

Explore related subjects

Angiolymphoid Hyperplasia with EosinophiliaChildDiagnosis, DifferentialEar DiseasesEar NeoplasmsFemaleHumansMaleMiddle AgedNose DiseasesNose NeoplasmsCase ReportsEnglish AbstractJournal Article

Keep this discovery

Explore connections, maps & timelines

BibTeXRIS

H Hess, B Ströhmann, H Martin. 1991. [Kimura disease--2 case reports].. https://doi.org/10.1055/s-2007-998074

Cite the original work for its findings. Save a collection to share your selection of sources.

KEEP EXPLORING

Related citations

PubMed2003

Kimura disease in a patient with renal allograft failure secondary to chronic rejection.

Recent studies suggest that CD4(+ )T helper 2 (Th2) cell proliferation and overexpression of Th2 cytokines may play an important role in the development of Kimura disease. Chronic rejection of a renal allograft by the indirect allo recognition pathway is also induced by Th2 cytokines. We report a 12-year-old boy who had presented with nephrotic syndrome 10 years previously. He was found to have focal segmental glomerulosclerosis, which was attributed to vesicoureteral reflux, and he underwent renal transplantation at the age of 5 years. Allograft dysfunction secondary to chronic rejection was noted by 2 years post transplant, after which continuous ambulatory peritoneal dialysis was instituted. After discontinuation of immunosuppressive therapy, he progressively developed peripheral eosinophilia and eczema, followed by cervical lymphadenopathy and then epitrochlear lymphadenopathy. Kimura disease was diagnosed on lymph node biopsy. Our patient demonstrated that Kimura disease can occur after renal allograft failure secondary to chronic rejection. Both disorders involve the Th2-dominant immune response, according to previous observations.

Angiolymphoid Hyperplasia with Eosinophilia↗