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Anencephaly and maternal common cold.

K Kurppa·P C Holmberg·E Kuosma·T Aro·L Saxén
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Abstract

To study the risk of anencephaly related to common cold during pregnancy, a case-control study was made. The series comprised 393 Finnish mothers of anencephalic children and their time-area-matched controls in the period 1964 through 1982. Seventy mothers of anencephalic infants and 17 controls had reported common cold in the first trimester [adjusted odds ratio 4.5; 95% confidence interval (2.2-9.1)]. Reported common cold in the second trimester was not associated with anencephaly. As suggested by our previous cohort study in the same population, a true viral influenza resembling "common cold" might not explain the observed association.

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AnencephalyCase-Control StudiesCommon ColdConfounding Factors, EpidemiologicFemaleHumansOdds RatioPregnancyPregnancy Complications, InfectiousPregnancy Trimester, FirstPregnancy Trimester, SecondRegression AnalysisRetrospective StudiesRisk FactorsJournal Article

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K Kurppa, P C Holmberg, E Kuosma, T Aro, L Saxén. 1991. Anencephaly and maternal common cold.. https://doi.org/10.1002/tera.1420440109

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PubMed2006

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