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A modified pulse sequence for in vivo diffusion imaging with reduced motion artifacts.

P V Prasad·O Nalcioglu
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Abstract

A modified spin-echo diffusion imaging pulse sequence incorporating bipolar gradients that is less sensitive to macroscopic motion-induced artifacts is presented. Expressions for apparent diffusion coefficient in the presence of microcirculation and macroscopic motions and contrast-to-noise ratio in the diffusion map are derived. Diffusion coefficients of liquid phantoms have been measured using a 1.5-T GE Signa system. Experiments performed to demonstrate the immunity to motion-induced errors are reported. Brain images from human volunteer have also been included to show the potential clinical application of the proposed pulse sequence.

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BrainHumansMagnetic Resonance ImagingModels, StructuralMovementJournal ArticleResearch Support, U.S. Gov't, P.H.S.

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P V Prasad, O Nalcioglu. 1991. A modified pulse sequence for in vivo diffusion imaging with reduced motion artifacts.. https://doi.org/10.1002/mrm.1910180113

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