Sleep-wakefulness patterns in the helpless rat.

J Adrien; C Dugovic; P Martin

doi:10.1016/0031-9384(91)90041-l

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PubMed · 2062895

Sleep-wakefulness patterns in the helpless rat.

J Adrien·C Dugovic·P Martin

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Abstract

Sleep-wakefulness patterns were analyzed during a 15-day period in the rat, in relation to induction of helplessness. After a session of inescapable electric footshocks, rats did exhibit escape deficits in avoidance conditioning as classically described, and their spontaneous sleep-wakefulness patterns were not different from those of controls. However, reduced PS latency and increased PS amounts were observed in the helpless group after shuttle-box sessions, especially during the initial period after the induction of helplessness. Such modifications of PS latency and PS amounts are evocative of the sleep impairments classically observed in endogenous depression.

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Animals Arousal Avoidance Learning Circadian Rhythm Escape Reaction Helplessness, Learned Male Mental Recall Rats Rats, Inbred Strains Sleep Stages Wakefulness Journal Article

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J Adrien, C Dugovic, P Martin. 1991. Sleep-wakefulness patterns in the helpless rat.. https://doi.org/10.1016/0031-9384(91)90041-l

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