Imaging cells with the atomic force microscope.

H J Butt; E K Wolff; S A Gould; B Dixon Northern; C M Peterson; P K Hansma

doi:10.1016/1047-8477(90)90098-w

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PubMed · 2100150

Imaging cells with the atomic force microscope.

H J Butt·E K Wolff·S A Gould·B Dixon Northern·C M Peterson·P K Hansma

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Abstract

Different types of cells have been imaged with the atomic force microscope. The morphology of the archaebacterium Halobacterium halobium in its dry state was revealed. On a leaf of the small Indian tree Lagerstroemia subcostata a stoma was imaged. The lower side of a water lily leaf was imaged in water showing features down to 12 nm. Finally, fixed red and white blood cells were imaged in buffer showing features down to 8 nm. The images demonstrate that atomic force microscopy can provide high-resolution images of cell surfaces under physiological conditions.

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Animals Erythrocytes Halobacterium Lymphocytes Microscopy Plants Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

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H J Butt, E K Wolff, S A Gould, B Dixon Northern, C M Peterson, P K Hansma. Imaging cells with the atomic force microscope.. https://doi.org/10.1016/1047-8477(90)90098-w

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