Plasma von Willebrand factor concentration and thyroid function in dogs.

S Avgeris; C D Lothrop; T P McDonald

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PubMed · 2107158

Plasma von Willebrand factor concentration and thyroid function in dogs.

S Avgeris·C D Lothrop·T P McDonald

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Abstract

Plasma von Willebrand factor antigen concentration was determined in 15 dogs with suspected hypothyroidism, in 1 dog with hyperthyroidism, and in 14 euthyroid dogs. The mean +/- SEM von Willebrand factor:antigen concentration in hypothyroid dogs (47.1% +/- 12.6%) was significantly decreased (P less than 0.0005), compared with that in euthyroid dogs (94.7 +/- 5.6%). Four hypothyroid dogs were given thyroxine for 1 month and all 4 had an increase in von Willebrand factor:antigen concentration. The plasma von Willebrand factor:antigen concentration was 200% in the hyperthyroid dog. Seemingly, reduced concentrations of plasma von Willebrand factor:antigen can be found in dogs in association with congenital von Willebrand disease or with von Willebrand disease acquired through hypothyroidism.

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Animals Dog Diseases Dogs Female Hyperthyroidism Hypothyroidism Male Radioimmunoassay Thyroid Gland Thyrotropin Thyrotropin-Releasing Hormone Thyroxine von Willebrand Diseases von Willebrand Factor Comparative Study Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S.

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S Avgeris, C D Lothrop, T P McDonald. 1990-03-15. Plasma von Willebrand factor concentration and thyroid function in dogs.. https://pubmed.ncbi.nlm.nih.gov/2107158/

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