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PubMed · 2190025

[inflammatory reaction and laboratory tests: granulocyte elastase].

I Sakurabayashi·K Shimanuki·A Shinpo·S Ishii
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Abstract

The role in the so called inflammatory response of the polymorphonuclear granulocyte elastase (PMN elastase, EC 3.4.21.37) has been well established. Elastase, a neutral protease stored in the lysosomes of neutrophils and monocytes, is extracellularly released during the process of phagocytosis, and bound to alpha 1-proteinase inhibitor (E-alpha 1-PI complex). This complex can be quantified by an immunoassay. PMN elastase has been shown to be a sensitive and specific marker for the early diagnosis of inflammation and prediction of inflammatory complications.

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Clinical Enzyme TestsGranulocytesHumansInflammationPancreatic ElastaseEnglish AbstractJournal ArticleReview

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I Sakurabayashi, K Shimanuki, A Shinpo, S Ishii. 1990. [inflammatory reaction and laboratory tests: granulocyte elastase].. https://pubmed.ncbi.nlm.nih.gov/2190025/

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