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PubMed · 2210796

[Thrombocyte growth factor].

C Buck·M Montenarh
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Abstract

PDGF is one of the principal mitogens for cultured cells of mesenchymal origin. Apart from aggregated platelets PDGF can be secreted by a number of cells. There is a striking homology between the amino-acid sequence of PDGF and that of a transforming protein of simian-sarcoma virus. PDGF is an important chemotactic protein for cells implicated in wound healing. Furthermore, recent publications suggest a possible role in the pathogenesis of several diseases. This article summarizes studies and recent findings on the structure, biology, and functional role of PDGF.

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AnimalsBlood PlateletsHumansPlatelet-Derived Growth FactorEnglish AbstractJournal ArticleResearch Support, Non-U.S. Gov'tReview

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C Buck, M Montenarh. 1990. [Thrombocyte growth factor].. https://pubmed.ncbi.nlm.nih.gov/2210796/

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