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Potassium channels expressed from rat brain cDNA have delayed rectifier properties.

W Stühmer·M Stocker·B Sakmann·P Seeburg·A Baumann·A Grupe·O Pongs
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Abstract

Injection into Xenopus oocytes of RNA synthesized in vitro using the rat brain cDNA RCK1 as a template or nuclear injection of the cDNA results in the expression of functional potassium channels. These channels exhibit properties similar to those of the non-inactivating delayed rectifier channel found in mammalian neurons and other excitable cells.

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4-AminopyridineAminopyridinesAnimalsCell MembraneCerebral CortexDNAElapid VenomsElectric ConductivityFemaleGene Expression RegulationHistamine ReleaseMembrane PotentialsOocytesPeptidesPotassiumPotassium ChannelsRatsTetraethylammoniumTetraethylammonium CompoundsXenopusComparative StudyJournal ArticleResearch Support, Non-U.S. Gov't

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W Stühmer, M Stocker, B Sakmann, P Seeburg, A Baumann, A Grupe, O Pongs. 1988-12-19. Potassium channels expressed from rat brain cDNA have delayed rectifier properties.. https://doi.org/10.1016/0014-5793(88)81015-9

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