Neuroleptic-resistant schizophrenics.

Abstract

According to Crow's postulated positive-negative distinction, negative symptoms of schizophrenia are less responsive to neuroleptic drugs. Not all research evidence supports that expectation, however, so that neuroleptics need not be withheld from any schizophrenic patients. Other aspects of Crow's hypothesized distinction have indicated possible promising results, but more research is required.