Disturbed endocrine function in the psychoses. II: Discriminant function analysis of multihormone data.

L J Whalley; J E Christie; D H Blackwood; J Bennie; H Dick; I M Blackburn; G Fink

doi:10.1192/bjp.155.4.462

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Disturbed endocrine function in the psychoses. II: Discriminant function analysis of multihormone data.

L J Whalley·J E Christie·D H Blackwood·J Bennie·H Dick·I M Blackburn·G Fink

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Abstract

Discriminant function analyses were performed on plasma concentrations of prolactin, growth hormone, cortisol, TSH, and the neurophysins measured over 17 hours in 70 newly admitted drug-free psychiatric patients and 35 control subjects. The hormone data distinguished between patients with different classes of drug-free psychosis (26 schizophrenic, 12 with manic disorder, 10 with major depressive disorder, psychotic subtype, 9 with schizoaffective mania (SAM]. Higher plasma cortisol and lower TSH concentrations separated eight of nine SAM patients from all others.

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Bipolar Disorder Depressive Disorder Discriminant Analysis Female Hormones Humans Hydrocortisone Male Neurophysins Prolactin Psychotic Disorders Schizophrenia Thyrotropin Journal Article

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L J Whalley, J E Christie, D H Blackwood, J Bennie, H Dick, I M Blackburn, G Fink. 1989. Disturbed endocrine function in the psychoses. II: Discriminant function analysis of multihormone data.. https://doi.org/10.1192/bjp.155.4.462

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