Methylscopolamine and conditioned location avoidance.

R N Hughes; N M Blampied; G J Anderson; G J Woollett

doi:10.1016/0091-3057(89)90492-9

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Methylscopolamine and conditioned location avoidance.

R N Hughes·N M Blampied·G J Anderson·G J Woollett

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Abstract

On alternate days, rats were confined to one side of a shuttlebox following IP administration of saline and to the other following the peripherally-acting muscarinic antagonist, methylscopolamine (1.2 mg/kg). They later avoided the side associated with the drug effect. By duplicating an earlier finding with centrally- and peripherally-acting scopolamine, this result identified aversive peripheral actions of the two drugs as mainly responsible for the effects observed.

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Animals Avoidance Learning Conditioning, Classical Exploratory Behavior Female Male Muscarinic Antagonists N-Methylscopolamine Rats Scopolamine Derivatives Journal Article

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R N Hughes, N M Blampied, G J Anderson, G J Woollett. 1989. Methylscopolamine and conditioned location avoidance.. https://doi.org/10.1016/0091-3057(89)90492-9

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